ontologyIndex - Reading Ontologies into R
Functions for reading ontologies into R as lists and manipulating sets of ontological terms - 'ontologyX: A suite of R packages for working with ontological data', Greene et al 2017 <doi:10.1093/bioinformatics/btw763>.
Last updated 12 months ago
7.02 score 6 stars 27 dependents 286 scripts 1.3k downloadsontologyPlot - Visualising Sets of Ontological Terms
Create R plots visualising ontological terms and the relationships between them with various graphical options - Greene et al. 2017 <doi:10.1093/bioinformatics/btw763>.
Last updated 12 months ago
4.48 score 5 dependents 50 scripts 373 downloadsontologySimilarity - Calculating Ontological Similarities
Calculate similarity between ontological terms and sets of ontological terms based on term information content and assess statistical significance of similarity in the context of a collection of terms sets - Greene et al. 2017 <doi:10.1093/bioinformatics/btw763>.
Last updated 11 months ago
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4.09 score 1 dependents 68 scripts 271 downloadsBeviMed - Bayesian Evaluation of Variant Involvement in Mendelian Disease
A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.
Last updated 9 months ago
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3.41 score 1 stars 17 scripts 651 downloadsSimReg - Similarity Regression
Similarity regression, evaluating the probability of association between sets of ontological terms and binary response vector. A no-association model is compared with one in which the log odds of a true response is linked to the semantic similarity between terms and a latent characteristic ontological profile - 'Phenotype Similarity Regression for Identifying the Genetic Determinants of Rare Diseases', Greene et al 2016 <doi:10.1016/j.ajhg.2016.01.008>.
Last updated 12 months ago
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2.78 score 6 scripts 257 downloadsIntervalSurgeon - Operating on Integer-Bounded Intervals
Manipulate integer-bounded intervals including finding overlaps, piling and merging.
Last updated 12 months ago
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2.73 score 1 dependents 18 scripts 344 downloadspaintmap - Plotting Paintmaps
Plots matrices of colours as grids of coloured squares - aka heatmaps, guaranteeing legible row and column names, without transformation of values, without re-ordering rows or columns, and without dendrograms.
Last updated 8 years ago
2.26 score 6 dependents 6 scripts 212 downloadsgsEasy - Gene Set Enrichment Analysis in R
R-interface to C++ implementation of the rank/score permutation based GSEA test (Subramanian et al 2005 <doi: 10.1073/pnas.0506580102>).
Last updated 12 months ago
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2.00 score 9 scripts 299 downloads