Changes in version 5.1 (2017-07-03)                   

  - New function, subset_variants, which retains only variants with data
    bearing upon pathogenicity.
  - Return posterior mean of omega even when not explicitly sampled in
    summary.BeviMed_m.

                  Changes in version 5.0 (2017-04-22)                   

  - bevimed_polytomous function added which enables application of
    BeviMed across multiple association models.
  - BeviMed objects now more general, representing results of inference
    with respect to the baseline model gamma = 0 and an arbitrary number
    of alternative association models - typically, one for each mode of
    inheritance. The $moi slot has been replaced with $models.
  - prob_pathogenic now returns a list when broken down by mode of
    inheritance/model.

                         Changes in version 4.3                         

  - Make BeviMed work smoothly when number of individuals or number of
    variants is 0.
  - Retain names of variants from columns of original allele count
    matrix.
  - Improvements to guide, with more detail on model selection.

                         Changes in version 4.2                         

  - Fixed bug in calculation of expected number of explaining variants
    by only including those with pathogenic configurations.

                  Changes in version 4.0 (2017-03-01)                   

  - Previous bevimed function now replaced by bevimed_m, with the _m
    indicating that it conditions on mode of inheritance.
  - bevimed now integrates over indicator of association (gamma) and
    mode of inheritance (m), allowing user to specify priors on
    probability of association and probability of dominance.
  - The BeviMed class object has been replaced by BeviMed_m, and a new
    BeviMed class has been introduced for inference with respect to all
    models: gamma 0 and gamma 1 under each mode of inheritance.
  - A new vignette with more detail called BeviMed Guide which relates
    the package to the paper.
  - Names used for summary statistics in summary objects have changed,
    see function help pages for details on current names.
  - printing a BeviMed object now shows conditional probabilities of
    pathogenicity for each mode of inheritance, and expected explained
    cases and expected explaining variants shown too.
  - Bug fixed in adaptive tuning for omega and phi proposals.

                  Changes in version 3.0 (2017-02-16)                   

  - Re-naming of parameters in bevimed function to match the names of
    variables in the paper (under submission).
  - The allele count matrix G should now be supplied as a matrix with
    rows corresponding to individuals, not variants.
  - expected_explained and explaining_variants functions have been
    added, respectively computing the expected number of cases with
    their disease explained by the given variants, and expected number
    of pathogenic variants present amongst cases.